CFR - Code of Federal Regulation

Code of Federal Regulation (CFR) is the coding system of the general and permanent rules, laws and regulations in United States. They become official after the publication in Federal Register by the executive departments and agencies of the federal government of the United States.

The CFR is published by the Office of the Federal Register, an agency of the National Archive and Records Administration.

The CFR is divided into 50 titles that symbolize different functional areas subject to Federal Regulation.

CFR is identifies by the citation, such as 21 CFR 210.1 would be read as, “Title 21, Part 210, Section 1” represent Status of Current Good Manufacturing Practice Regulations.

While new regulations are becoming effective constantly the printed volumes of the CFR are issued once each calendar year, on the following schedule:

Title 1 – 16 are updated on 1 January

Title 17 – 27 are updated on 1 April

Title 28 – 41 are updated on 1 July

Title 42 – 50 are updated on 1 October

As a Pharmaceutical Professional Title 21 is import for Food and Drugs.

21 CFR is further divided into parts which denote the specific regulation for the following enlisted categories:

Parts	Topics covered
1 – 100	Administrative issue and protection of Human Subjects
100	Foods
200	Labelling, cGMP and Controlled substance
300	Drugs for Human Use
500	Drugs for Veterinary Use
600	Biologicals
700	Cosmetics
800	Medical Device
1000 - 1400	Miscellaneous